Pilonidal cyst

Last updated: March 16, 2021

Summarytoggle arrow icon

A pilonidal cyst (intergluteal pilonidal disease) is a skin condition caused by local inflammation of the superior midline gluteal cleft, which may progress to a local abscess or fistula. It is currently hypothesized to be an acquired condition with local penetration of hair follicles and debris in stretched intergluteal pores. Affected individuals – typically obese, sedentary men with excessive body hair and a deep gluteal cleft – may be asymptomatic or present with mild local symptoms such as local oozing or erythema; however, abscesses can also cause severe pain. Pilonidal cysts are diagnosed based on patient history and clinical examination. To treat the condition, radical resection with secondary wound healing is usually necessary. Asymptomatic patients can be treated conservatively.

Epidemiologytoggle arrow icon

Epidemiological data refers to the US, unless otherwise specified.

Pathophysiologytoggle arrow icon

The exact mechanism is unknown, however, the current prevailing hypothesis is that pilonidal disease is an acquired condition.

  • Sitting or bending cause hair follicles, in vulnerable skin within a deep natal cleft, to stretch and break → formation of an open pore or pit. These open pores either collect debris or broken hair roots (from the head, back or buttocks).
  • Movement causes negative pressure (e.g., “suction effect”) and further penetration of hair into local subcutaneous tissue → formation of a pilonidal sinus [2]
  • These collections trigger local tissue inflammation within the pilonidal sinus → acute infection (abscess) or fistulae [3][4]

Risk factorstoggle arrow icon

  • Young men with excessive body hair
  • Obesity
  • Deep gluteal cleft
  • Poor anal hygiene/local irritation
  • Sedentary lifestyle
  • Family history

Clinical featurestoggle arrow icon

Differential diagnosestoggle arrow icon

The differential diagnoses listed here are not exhaustive.

Treatmenttoggle arrow icon

Conservative treatment

  • Indications
    • Asymptomatic patients
    • Postsurgical care of symptomatic patients
  • Approach
    • Improved local hygiene
    • Local hair control (e.g., laser epilation) [5]
    • Observation for signs of infection

Surgical treatment

Referencestoggle arrow icon

  1. Majeski J, Stroud J. Sacrococcygeal Pilonidal Disease. International Surgery. 2011; 96: p.144-147.doi: 10.9738/1393.1 . | Open in Read by QxMD
  2. Bailey HR, Billingham RP, Stamos MJ, Snyder MJ. Colorectal surgery. Elsevier Saunders ; 2012: p. 170
  3. Goel TC, Goel A. Practical Surgery Short Clinical Cases. Jaypee Brothers Medical Publishers ; 2015: p. 219
  4. Pilonidal sinus disease. Updated: December 1, 2003. Accessed: December 6, 2016.
  5. Ghnnam WM, Hafez DM. Laser Hair Removal as Adjunct to Surgery for Pilonidal Sinus: Our Initial Experience. J Cutan Aesthet Surg. 2011; 4 (3): p.192-195.doi: 10.4103/0974-2077.91251 . | Open in Read by QxMD
  6. Greenberg R, Kashtan H, Skornik Y, Werbin N. Treatment of pilonidal sinus disease using fibrin glue as a sealant. Techniques in Coloproctology. 2004; 8 (2).
  7. Steele SR, Perry WB, Mills S, Buie WD. Practice Parameters for the Management of Pilonidal Disease. Dis Colon Rectum. 2013; 59 (9): p.1021-1027.doi: 10.1097/DCR.0b013e31829d2616 . | Open in Read by QxMD

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