Ischemic hepatitis

Last updated: May 18, 2022

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Ischemic hepatitis refers to acute, diffuse liver injury due to hypoperfusion. The most common causes of hepatic hypoperfusion are cardiopulmonary failure and shock. Clinical presentation varies and may be asymptomatic or involve abdominal pain, nausea, vomiting, and anorexia. Diagnosis is established based on medical history (e.g., history of heart failure) and severely elevated serum aminotransferase levels, elevated LDH, and bilirubin levels. Management consists of treating the underlying condition and hemodynamic support.

Epidemiological data refers to the US, unless otherwise specified.

Pathophysiology of hepatic tissue hypoxia and necrosis:

The differential diagnoses listed here are not exhaustive.

There is no specific treatment for ischemic hepatitis.

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