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Bulbar palsy and pseudobulbar palsy

Last updated: October 6, 2020

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Bulbar palsy is a lower motor neuron palsy that affects the nuclei of the IXth, Xth, XIth, and XIIth cranial nerves. Pseudobulbar palsy is an upper motor neuron palsy that affects the corticobulbar tracts of the Vth, VIIth, IXth, Xth, XIth, and XIIth cranial nerves. Any condition which disrupts or damages the cranial nerve nuclei or corticobulbar tracts can cause bulbar or pseudobulbar palsy (e.g., stroke, multiple sclerosis, infections, brain stem tumors). Both bulbar and pseudobulbar palsy are seen mainly in men over 75 years old and present with dysarthria and dysphagia. In addition, patients with pseudobulbar palsy present with a lack of facial expression, difficulty chewing, and emotional lability. Lower motor neuron signs (atrophy and fasciculations of the tongue, absent gag reflex) differentiate bulbar palsy from pseudobulbar palsy, which presents with upper motor neuron signs (spastic tongue, exaggerated gag, and jaw jerk reflexes). Diagnosis is mainly clinical. CSF analysis and MRI of the brain help identify the etiology. Treatment is mainly supportive.

  • Age: 75–80 years
  • Sex: >

References:[1][2]

Epidemiological data refers to the US, unless otherwise specified.

Bulbar palsy Pseudobulbar palsy
Etiology
Pathophysiology
Clinical features

References:[3][4][4][5][6][7][8][9][10][11][12]

Bulbar palsy and pseudobulbar palsy are clinical diagnoses based on clinical features. Tests are performed to diagnose the underlying condition.

References:[13]

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